Publications

2020

 

45Mašková E, et al. Hypromellose – A traditional pharmaceutical excipient with modern applications in oral and oromucosal drug delivery. Journal of Controlled Release. https://doi.org/10.1016/j.jconrel.2020.05.045

44. Carobolante G, et al. Cow Milk and Intestinal Epithelial Cell-derived Extracellular Vesicles as Systems for Enhancing Oral Drug Delivery. Pharmaceutics. https://doi.org/10.3390/pharmaceutics12030226

43. Mantaj J and Vllasaliu D. Recent advances in the oral delivery of biologics. The Pharmaceutical Journal, January 2020, 304, 7933. doi:10.1211/PJ.2020.20207374

 

2019

42. Muraleetharan V, et al. Nanoparticle modification in biological media: implications for oral nanomedicines. RSC Advances 2019, 9, 40487-40497. https://doi.org/10.1039/C9RA08403G 

41. Perinelli D R, et al. PEGylation affects the self-assembling behavior of amphiphilic octapeptides. International Journal of Pharmaceutics 2019, 571, 118752. https://doi.org/10.1016/j.ijpharm.2019.118752

40. Yong J. et al. Delivery of nanoparticles across the intestinal epithelium via the transferrin transport pathway. Pharmaceutics 2019, 11(7): E298. https://doi.org/10.3390/pharmaceutics11070298

 

39. Perinelli D R, et al. Quaternary Ammonium Leucine-Based Surfactants: The Effect of a Benzyl Group on Physicochemical Properties and Antimicrobial Activity. Pharmaceutics 2019, 11(6):287. https://doi.org/10.3390/pharmaceutics11060287

38. Pazhanimala SK. Engineering Biomimetic Gelatin Based Nanostructures as Synthetic Substrates for Cell Culture. Appl Sci 2019, 9, 1583. https://doi.org/10.3390/app9081583

37. Perinelli D R, et al. Quaternary ammonium surfactants derived from leucine and methionine: novel challenging surface active molecules with antimicrobial activity. Journal of Molecular Liquids. Accepted 15/3/19. 10.1016/j.molliq.2019.03.083

36. Aprodu A, et al. Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics. Pharmaceutics 2019, 11(3), 127. doi:10.3390/pharmaceutics11030127

 

35. Pazhanimala S, et al. Electrospun Nanometer to Micrometer Scale Biomimetic Synthetic Membrane Scaffolds in Drug Delivery and Tissue Engineering: A Review. Appl Sci 2019, 9(5):910. https://doi.org/10.3390/app9050910

2018

34. Turcanu, MV, et al. Ultrasound and Microbubbles Promote the Retention of Fluorescent Compounds in the Small Intestine. 2018 IEEE International Ultrasonics Symposium, IUS 2018. IEEE Computer Society, Vol. 2018-October.

33. Mantaj J, et al. The Role of Basement Membrane in Intestinal Barrier to Absorption of Macromolecules and Nanoparticles. Mol Pharm 2018, 15(12):5802-5808 

32. Zhai J, et al. Ascorbyl Palmitate Hydrogel for Local, Intestinal Delivery of Macromolecules. Pharmaceutics 2018, 10(4):188. https://doi.org/10.3390/pharmaceutics10040188

31. Vllasaliu D, et al. Recent advances in oral delivery of biologics: nanomedicine and physical modes of delivery. Expert Opin Drug Deliv. 2018, 15:759-770. https://doi.org/10.1080/17425247.2018.1504017

30. Hashem L, et al. Intestinal uptake and transport of albumin nanoparticles: potential for oral delivery. Nanomedicine. 2018, 13:11. https://doi.org/10.2217/nnm-2018-0029

29. Cole H, et al. Chitosan nanoparticle antigen uptake in epithelial monolayers can predict mucosal but not systemic in vivo immune response by oral delivery. Carbohydr Polym. 2018, 190:248-254. https://doi.org/10.1016/j.carbpol.2018.02.084

28. Capel V, Vllasaliu D, et al. Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA. Drug Deliv. 2018, 25:644-653. https://doi.org/10.1080/10717544.2018.1440668

27. Perinelli D, et al. Lactose oleate as new biocompatible surfactant for pharmaceutical applications. Eur J Pharm Biopharm. 2018, 124:55-62. https://doi.org/10.1016/j.ejpb.2017.12.008   

2017

26. Perinelli, D, et al. Rhamnolipids as epithelial permeability enhancers for macromolecular therapeutics. Eur J Pharm Biopharm 2017, 119:419-425.

25. Bird J, et al. Neurotensin receptor 1 facilitates intracellular and transepithelial delivery of macromolecules. Eur J Pharm Biopharm 2017, 119:300-309

2016

24. Perinelli D, et al. Correlation among chemical structure, surface properties and cytotoxicity of N-acyl alanine and serine surfactants. Eur J Pharm Biopharm 2016, 109:93-102.

23. Lucarini S, et al. Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity. Eur J Pharm Biopharm 2016, 107:88-96.

22. Capel V, et al. Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency. Biochem Biophys Res Commun 2016, 477 (2):260-265.

2015

21. Byrne G, Vllasaliu D, et al. Live imaging of cellular internalization of single colloidal particle by combined label-free and fluorescence Total Internal Reflection Microscopy. Mol Pharm 2015, 12, (11):3862-70.

20. Daci A, et al. Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of Kosovar albanian epileptic patients. PloS one 2015, 10, (11):e0142408.

19. Shubber S, Vllasaliu D, et al. Mechanism of mucosal permeability enhancement of CriticalSorb. (Solutol. HS15) Investigated In Vitro in Cell Cultures. Pharm Res 2015, 32, (2):516-27.

2014

18. Bannunah A, Vllasaliu D, et al. Mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Mol Pharm 2014, 11, (12):4363-73.

17. Vllasaliu D and Singh I. Particle characterisation in drug delivery. European Pharmaceutical Review 09/2014.

16. Garnett M, Vllasaliu D, et al. Drug delivery - epithelial cell models for drug transport and toxicology studies. Biochemist 06/2014; 36(3).

15. Vllasaliu D, et al. Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules. Exp Cell Res 2014, 323, (1):218-31.

14. Vllasaliu D, et al. PEGylated nanomedicines: recent progress and remaining concerns. Expert Opin Drug Deliv 2014, 11, (1):139-54.

 

2013

13. Fowler R, Vllasaliu D, et al. Uptake and transport of B12-conjugated nanoparticles in airway epithelium. J Control Release 2013, 172:374-381.

12. Vllasaliu D, et al. Folic acid conjugated chitosan nanoparticles for tumor targeting of therapeutic and imaging agents. Pharm Nanotechnol 2013, 1:184-203.

11. Fowler R, Vllasaliu D, et al. Nanoparticle transport in epithelial cells: pathway switching through bioconjugation. Small 2013, 9:3282-94.

10. Vllasaliu D, et al. Epithelial toxicity of alkylglycoside surfactants. J Pharm Sci 2013, 102:114-25.

2012

9. Casettari L, Vllasaliu D, et al. Biomedical applications of amino acid-modified chitosans: A review. Biomaterials 2012, 33, (30):7565-7583.

8. Vllasaliu D, et al. Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. Int J Pharm 2012, 430, (1-2):151-160.

7. Moradi E, Vllasaliu D, et al. Ligand density and clustering effects on endocytosis of folate modified nanoparticles. RSC Advances 2012, 2:3025-3033.

6. Vllasaliu D, et al. Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochem Biophys Res Commun 2012, 418, (1):128-133.

5. Vllasaliu D, et al. Fc-mediated transport of nanoparticles across airway epithelial cell layers. J Control Release 2012, 158, (3):479-486.

4Casettari L, Vllasaliu D, et al. PEGylated chitosan derivatives: Synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science 2012, 37, (5): 659-685

2011

3. Vllasaliu D, et al. Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochem Biophys Res Commun 2011, 415, (4):579-585.

2. Casettari L, Vllasaliu D, et al. Effect of PEGylation on the Toxicity and Permeability Enhancement of Chitosan. Biomacromolecules 2011, 11:2854-2865.

2010

1. Vllasaliu D, et al. Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. Int J Pharm 2010, 400, (1-2):183-193.